Extraction of Curcumin from Raw Turmeric (Curcuma longa.) – A Comparative Study, Using Soxhlet, Chemical, Chromatographic, and Spectroscopic Methods and Determining its Bioavailability

Abstract

Turmeric (Curcuma longa) is a broadly grown perennial herb, and its organic residences are attributed to the content material of curcuminoids, which abundantly exist in Turmeric. Curcumin, is a crystalline polyphenol, which is extracted from turmeric, and contains various phytochemicals such as desmethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC). In this study, specific types of samples of Curcuma longa species (Turmeric) have considered for the extraction of Curcumin, which has highly potential and established medical benefits. According to a human tissue-based angiogenesis, curcumin was found to be anti-angiogenic. This experiment is carried out to compare and investigate the best extraction strategy and the ideal sample of Turmeric which gives out immoderate and optimum yield. Soxhlet extraction technique is carried out to evaluate the results of those obtained from curcumin extraction with dissolving method with assistance of liquid chromatography. One of the influential solvents includes methanol for dilution and extraction procedure. HPLC is completed for the calculation of bioavailability of curcumin, UV- VIS spectroscopy is used for the determination of absorbance. While there are an extensive range of biological experiments about this study, the pharmacological and chemical aspects are comparatively scarce. With this comparative study, the average curcumin consumption for enhancement of everyday diet can be obtained.